Dr. Doria Talks Finding New Kidney Disease Treatment with PERL

My name is Allesandro Doria and I
work in the in the research division of the Joslin. My research is specifically on
diabetic complications and now how to find new ways to prevent this
problem in people with diabetes and one particular focus that we have
is on kidney complications and we made a lot of progress in a
trying to reduce this problem by better quality control and by better control blood pressure. However still a significant number of people with
diabetes end up developing kidney disease and requiring
kidney transplant to survive. One study that we are doing and we are really excited about is
called preventing early reno loss in diabetes. What we’re
trying to do is to see whether medication that is commonly used
to decrease uric acid in blood can
also work to slow down or prevent the kidney
function loss in people with type 1 diabetes and
this research is based on some findings that we have here
at the Joslin; we found that people with the relatively high uric acid
levels in blood had increased risk of losing kidney
function and so we are trying to see whether by decreasing uric acid we can actually prevent this problem
from happening and if this is the results will have a new
treatment for kidney complications that we can add good lesson in controlling to control
blood pressure. This is a clear example of translating research that happened here at the Joslin
to new therapies and I’d like to thank all the people who will be supporting the
clinic and the research division for their help because without
that this message would not be possible.

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